Antimicrobial Use- Related Articles of Interest

Urinary Tract Infection (UTI)

Shirley D et al. Optimizing Inpatient Urine Culture Ordering Practices Using the Electronic Medical Record: A Pilot Study. Infect Control Hosp Epidemiol. 2017; 38(4): 486-488.  Abstract

Kiyatkin D et al. Impact of Antibiotic Choices Made in the Emergency Department on Appropriateness of Antibiotic Treatment of Urinary Tract Infections in Hospitalized Patients. J Hosp Med. 2016; 11(3): 181-4. Abstract

Sarg M et al. Impact of Changes in Urine Culture Ordering Practice on Antimicrobial Utilization in Intensive Care Units at an Academic Medical Center. Infect Control Hosp Epidemiol. 2016; 37(4): 448-54.  Abstract

 Asymptomatic Bacteriuria (ASB)

Lamb MJ et al. Elimination of Screening Urine Cultures Prior to Elective Joint Arthroplasty. Clin Infect Dis. 2017; 64(6):806-809. Abstract
Collins CD. Impact of an Antimicrobial Stewardship Care Bundle to Improve the Management of Patients with Suspected or Confirmed Urinary Tract Infection. Infec Control Hosp Epidemiol. 2016;1-3. Abstract
Hartley SE et al. Evaluating a Hospitalist-Based Intervention to Decrease Unnecessary Antimicrobial Use in Patients with Asymptomatic Bacteriuria. Infect Control Hosp Epidemiol. 2016; 37: 1044-1051. Abstract
Trautner BW wt al Effectiveness of an Antimicrobial Stewardship Approach for Urinary Catheter-Associated Asymptomatic Bacteriuria. JAMA Intern Med. 2015; 175 (7):1120-1127. Abstract
Zalmanovici TA et a. Antibiotic for asymptomatic bacteriuria. Cochrane Database Syst Rev. 2015: CD009534. Abstract
Hartley S et al. Overtreatment of Asymptomatic Bacteriuria: Identifying Targets for Improvement. Infec Control Epidemiol. 2014; 00:1-4. Abstract
Leis JA et al. Reducing Antimicrobial Therapy for Asymptomatic Bacteriuria among Noncatheterized Inpatients: A Proof-of-Concept Study. Clin Infect Dis. 2014; 58 (7): 980-983. Abstract
Kelly D et al Evaluation of an Antimicrobial Stewardship Approach to Minimize Overuse of Antibiotics in Patients with Asymptomatic Bacteriuria. Infect Control Hosp Epidemiol. 2014; 35:193-5. Abstract
Hooten TM et al. Diagnosis, Prevention, and Treatment of Catheter- Associated Urinary Tract Infection in Adults: 2009 International Clinical Practice Guidelines from the Infectious Diseases Society of America. Clin Infect Dis. 2010; 50:625-663. Abstract
Nicolle LE et al. Infectious Diseases Society of America Guidelines for the Diagnosis and Treatment of Asymptomatic Bacteriuria in Adults. Clin Infect Dis. 2005; 40: 643-54. Abstract
Nicolle LE. Asymptomatic Bacteriuria in the elderly, Infect Dis Clin North Am. 1997; 11: 647-62. Abstract


Madaras-Kelly, KJ et al. Total duration of antimicrobial therapy in veterans hospitalized with uncomplicated pneumonia: Results of a national medication utilization evaluation. J Hosp Med. 2016 11(12): 832–839. Abstract

Treatment Duration in CAP

Foolad F, Huang A et al. A Multicentre Stewardship Initiative to Decrease Excessive Duration of Antibiotic Therapy for the Treatment of Community-Acquired Pneumonia. Journal of Antimicrobial Chemotherapy, dky021. Published Online 16 February 2018. Abstract

Foolad F, Huang A et al.  Impact of a Multi-faceted Stewardship Intervention on Duration of Antibiotic Therapy for the Treatment of Community-Acquired Pneumonia. ID Week; 2016 Oct 26-30; New Orleans, LA. Abstract
Haas MK, Dalton K, Knepper BC et al. Effects of a Syndrome Specific Antibiotic Stewardship Intervention for Inpatient Community Acquired Pneumonia. Open Forum Infect Dis. 2016:3(4).ofw186 Abstract
Li DX et al. Sustained Impact of an Antimicrobial Intervention for Community-Acquired Pneumonia. Infect Control Hosp Epidemiol 2016; 37:1243-1246. Abstract
Unranga A, Espana P, Bilbao et al. Duration of Antibiotic Treatment in Community-Acquired Pneumonia: A Multicenter Randomized Clinical Trial. JAMA Intern Med. 2016;176(9):1257-65. Abstract
Avdic E, Cuschinotto LA, Hughes AH, et al. Impact of an antimicrobial stewardship intervention on shortening the duration of therapy for community-acquired pneumonia. Clin Infect Dis 2012;54 (11):1581-7. Abstract
Dimopoulos G, Mathaiou DK, et al. Short versus long-course antibacterial therapy for community-acquired pneumonia: a meta-analysis. Drugs. 2008;68(13):1841-54. Abstract
Li JZ, Winston LG, Moore DH, Bent S. Efficacy of short-course antibiotic regimens for community-acquired pneumonia: a meta-analysis. Am J Med. 2007;120 (9):783-90. Abstract
File TM Jr. Mandell LA, et al. Gemifloxacin once daily for 5 days versus 7 days for the treatment of community-acquired pneumonia: a randomized, multicenter, double-blind study. J Antimicrob Chemother 2007;60:112-20.
Moussaoui R, et al. Effectiveness of discontinuing antibiotic treatment after three days versus eight days in mild to moderate-severe community-acquired pneumonia: randomized, double blind study. BMJ 2006;332:1335.
Dunbar LM, Wunderink RG et al. High-dose, short-course levofloxacin for community-acquired pneumonia: a new treatment paradigm. Clin Infect Dis 2003;37:752-60. Abstract
Leophante P, Choutet P, Gaillat J, et al. Efficacy of a ten day course of ceftriaxone compared to a shortened five day course in the treatment of community-acquired pneumonia in hospitalized adults with risk factors. Med Mal Infect 2002;32:369-81. Abstract


Chen JI, et al. Outcomes of healthcare-associated pneumonia empirically treated with guideline-concordant regimens versus community-acquired pneumonia guideline –concordant regimens for patients admitted to acute care wards from home. Ann Pharmacother; 47(1):9-19. Abstract
Chalmers J, et al. Healthcare-associated pneumonia does not accurately identify potentially resistant pathogens: a systematic review and meta-analysis. Clin Infect Dis 2014; 58:330-9. Abstract
Labelle AJ, et al. A comparison of culture –positive and culture negative healthcare-associated pneumonia. Chest 2010;137: 1130-1137. Abstract
Schlueter M, et al. Practice patterns for antibiotic de-escalation in culture-negative healthcare-associated pneumonia. Infection 2010; 38:357-62. Abstract