References:
General Hematology/Oncology
- Larcher, R. et al. Peripherally Inserted Central Venous Catheter (PICC) Related Bloodstream Infection in Cancer Patients Treated with Chemotherapy Compared with Noncancer Patients: A Propensity-Score-Matched Analysis. Cancers 2023.
- A retrospective analysis examined 721 PICCs in 627 patients to evaluate risk of infection in patients with cancer treated with chemotherapy who are immunocompromised. After propensity-score matching, PICCR-BSI incidence rate was 2.6/1,000 catheter days in cancer patients and 1.0/1,000 catheter days in non-cancer patients (p< 0.05). However, after adjusting for variables resulting in an imbalance between groups after propensity-score matching, only the number of PICC lumens was independently associated with PICCR-BSI (adjusted hazard ratio 1.81, 95% confidence interval: 1.01–3.22; p = 0.04).
- She, R. et al. Comparison of Infection Rates Between Single-Lumen and Double-Lumen Chest Ports Among Patients with Cancer: A Propensity Score Matching Analysis. J Vasc Interv Radiol 2024.
- A retrospective analysis of 2,573 adult oncologic patients who received either a single lumen (N=841) or double lumen (N=1,732) chest port. The port infection rate of the double lumen group was significantly higher than that of the single lumen group (0.232 vs 0.113 infections per 1,000 catheter-days; P = .001). Analysis demonstrated that use of a double lumen port was an independent risk factor of port infection (sub-distribution hazard ratio, 2.30; 95% CI, 1.33-3.78; P = .002).
Solid Tumor Malignancy
- Fukuda, S. et al. Use of Double-Lumen Peripherally Inserted Central Catheters for Safer Perioperative Management of Esophageal Cancer Patients. J Vasc Access 2015.
- 40 thoracic esophageal cancer patients requiring central venous catheterization during the perioperative period were assigned to the double lumen-PICC (4.5-French, 60-cm) group or the double lumen-CICC (16-gauge, 30-cm) group, with 1:1 randomization. The secondary lumen of the double lumen-PICCs performed as well as the secondary lumen of the double lumen-CICCs with acceptable safety during the relatively short perioperative period of these thoracic esophageal cancer patients