References
- Avdic E, et al. Impact of an Antimicrobial Stewardship Intervention on Shortening the Duration of Therapy for Community-acquired Pneumonia. Clin Infec Dis 2012.
- Reduced treatment duration of CAP with educational lectures based on survey results, and post-prescription pharmacy review with verbal feedback
- Ciarkowski CE, et al. A Pathway for Community-Acquired Pneumonia with Rapid Conversion to Oral Therapy Improves Health Care Value. Open Forum Infect Dis 2020.
- This study noted a shorter length of IV antibiotic therapy when a clinical decision support-driven CAP pathway was implemented, along with active antimicrobial stewardship review.
- Foolad F, et al. A Multi-center Stewardship Initiative to Decrease Excessive Duration of Antibiotic Therapy for the Treatment of Community Acquired Pneumonia. J Antimicro Chemo 2018
- Treatment duration for CAP was reduced by updating institutional CAP guidelines, providing educational sessions and performing daily audit and feedback on appropriate treatment duration for CAP patients.
- Giesler DL, et al. Reducing Overuse of Antibiotics at Discharge Home: A Single-Center Mixed Methods Pilot Study. Am Journ Inf Con 2022.
- A pharmacist-facilitated antibiotic timeout at time of hospital discharge was feasible and holds promise as a method to improve antibiotic use at discharge.
- Petty LA, et al. Impact of Updated ATS/IDSA CAP Guidelines on Duration of Antibiotics. Open Forum Inf Dis 2022.
- Among patients hospitalized with pneumonia, two thirds received an excess antibiotic duration. Prior to the updated IDSA guidelines, the 5-day treatment rate was improving for HCAP and pCAP - suggesting the 2019 guidelines did not have an added effect on improving antibiotic duration.
- Vaughn V, et al. Antibiotic Stewardship Strategies and Their Association with Antibiotic Overuse After Hospital Discharge: An Analysis of the Reducing Overuse of Antibiotics at Discharge (ROAD) Home Framework. Clin Inf Dis 2022.
- Antibiotics are frequently prescribed and overprescribed at hospital discharge, leading to patient harm. In 2019, a total of 39 hospitals were surveyed for their antibiotic stewardship strategies around discharge for patients with CAP and UTI. The more stewardship strategies reported, the lower a hospital’s antibiotic overuse at discharge.
- Vaughn V, et al. Excess Antibiotic Treatment Duration and Adverse Events in Patients Hospitalized with Pneumonia. Annals of Int Med 2019.
- Patients hospitalized with pneumonia often receive excess antibiotic therapy. Excess antibiotic treatment was associated with patient-reported adverse events.
- Vaughn V, et al. A Statewide Collaborative Quality Initiative to Improve Antibiotic Duration and Outcomes in Patients Hospitalized with Uncomplicated Community-Acquired Pneumonia. Clin Inf Dis 2022.
- Community-acquired pneumonia (CAP) is a common cause for hospitalization and antibiotic overuse. Across diverse hospitals, Michigan Hospital Medicine Safety Consortium (HMS) participation was associated with more appropriate use of short-course therapy and fewer adverse events in hospitalized patients with uncomplicated CAP.
- Yogo N, et al. Intervention to Reduce Broad-Spectrum Antibiotics and Treatment Durations Prescribed at the Time of Hospital Discharge: A Novel Stewardship Approach. Infect Contol Hosp Epidemio 2017.
- Reduced antibiotic duration prescribed at discharge by developing a guideline for antibiotic selection and treatment duration and performing pharmacy audit and feedback of discharge prescriptions