Jump to navigation
Develop, Share, and Integrate Institutional Guidelines for Patients with Sepsis - References
References
- Alberto, L. et al. Screening for sepsis in general hospitalized patients: a systematic review. J Hosp Infect 2017.
- A systematic review of literature which found that paper-based, nurse-led screening tools for sepsis appear to be more sensitive in the identification of septic patients.
- Dale, C. et al. Order set usage is associated with lower hospital mortality in patients with sepsis.Crit Care Explorations 2023.
- A retrospective, observational cohort study which found that the use of a sepsis order set(“Sepsis Management” order) was independently associated with lower hospital mortality in patients hospitalized with sepsis.
- Damiani, E. et al. Effect of performance improvement programs on compliance with sepsis bundles and mortality: a systematic review and meta-analysis of observational studies. PLoS One 2015.
- Performance improvement programs are associated with increased adherence to resuscitation and management sepsis bundles and with reduced mortality in patients with sepsis, severe sepsis, or septic shock.
- Dooley, K. et al. Improving hospital sepsis care using PAs and NPs on a rapid response team.JAAPA 2022
- Using a sepsis rapid response team with physician associates/assistants(PAs) and NPs improved hospital adherence to sepsis evaluation and order set use from 48% to 86%.
- Ju, T. et al. Sepsis Rapid Response TeamsCrit Care Clin 2018 .
- Using hospital-wide initiatives consisting of multidisciplinary education, training, and specific resource utilization, such teams have been found to improve patient outcomes for patients at risk of having or who have sepsis.
- Singer, M. et al. The Third International Consensus Definitions for Sepsis and Septic Shock(Sepsis-3).JAMA 2016.
- These updated Sepsis definitions and clinical criteria should replace previous definitions, offer greater consistency for epidemiologic studies and clinical trials, and facilitate earlier recognition and more timely management of patients with sepsis or at risk of developing sepsis.
- Tarabichi, Y.et al. Improving Timeliness of Antibiotic Administration Using a Provider and Pharmacist Facing Sepsis Early Warning System in the Emergency Department Setting: A Randomized Controlled Quality Improvement Initiative*Crit Care Med 2022.
- Display of an electronic health record–based sepsis early warning system–triggered flag combined with electronic health record–based pharmacist notification was associated with shorter time to antibiotic administration without an increase in undesirable or potentially harmful clinical interventions.
- Threat. D.L., et al. Improving sepsis bundle implementation times: A nursing process improvement approach.Nursing Care Qual 2020.
- A Performance Improvement project focusing on implementing an ER Nurse Sepsis Identification Tool, leadership buy-in, and SIRS education led to a decrease in time to bundle compliance in the ED.
- Thursky, K. et al. Implementation of a whole of hospital sepsis clinical pathway in a cancer hospital: impact on sepsis management, outcomes and costs. BMJ Open Quality 2018.
- Implementation of a whole hospital clinical pathway for the management of sepsis was associated with significant improvement in patient outcomes and reduced costs.
